Association between systemic lupus

Recent research has found an association between certain lupus patients (especially those with lupus nephritis) and an impairment in degrading neutrophil extracellular traps. Discoid Lupus is confined to the skin, whereas systemic lupus may involve any organ system in the body, as well as the skin. The disease mainly involves the skin, joints, kidneys, blood cells, and nervous system.
People with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. The signs and symptoms of lupus that you experience will depend on which body systems are affected by the disease. Moreover, first-degree relatives (mother, father, brother, sister) of people with lupus have an eightfold to ninefold increased risk of having lupus compared with the general public.